We can use cofactor expansion with respect to any column or any row. So usually we choose the column or row with the most number of 0 to simplify the calculation.
For this question, I expand at second row since there are 4 zeros there. Then, I expand the submatrix by picking the row with most number of zero too but need to take care of the sign.

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Part (b) require some properties of determinant, namely switching two rows/columns changes the sign of determinant and multiple of rows/columns can be added without changing the determinant value. Let me denote the question as

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Let E_1 denote the elementary operation of switching R1(row 1) and R3 of B. E_2 be (R2-R4) and E_3 be (R5-R2). Then,
Hope you can proceed to find det(C). For more information on the properties of determinant, you can try these websites:
http://en.wikipedia.org/wiki/Determinant
http://mathworld.wolfram.com/Determinant.html